What is Mechanica Natura?

Mechanica Natura is an educational reference that organises published research on nutraceuticals in the context of cancer and its treatment. It brings together evidence, biological pathways, pharmacokinetics, safety considerations, and formulation information in one structured system. It does not provide medical advice or recommend treatment.

What are Contain, Starve, Weaken, Attack, and Protect?

These are the five Level 1 roles in the Mechanica Natura Functional Framework. They are research-classification labels used to group pathways by broad biological objective, making it easier to navigate how compounds have been studied. They are not treatment stages, instructions, or claims that a compound will produce those effects in a person.

How are compounds assigned to Framework roles?

A compound is mapped to a role only where the literature reviewed supports a relevant compound–pathway relationship within the site’s stated inclusion criteria. The underlying pathways are grouped into more specific Level 2 mechanism categories, while the Level 1 role provides the broader context. A compound may be mapped to one role, several roles, or none in a particular area.

What does “human,” “animal,” or “in vitro” evidence mean?

Human evidence comes from studies involving people and has the greatest direct clinical relevance, although study quality and outcomes can still vary. Animal evidence can help establish biological plausibility but does not prove the same effect will occur in humans. In vitro evidence comes from laboratory cell models and shows what may happen under controlled conditions, often at concentrations that may not be achievable through normal oral use.

Does a citation mean a claim has been clinically proven?

No. A citation means the linked source reported the finding described and that the evidence has been placed in the appropriate tier. It does not necessarily mean the result has been replicated, represents scientific consensus, or translates into a meaningful clinical outcome. Reviews, laboratory studies, observational studies, and clinical trials do not all carry the same evidential weight.

How are products selected for the Sourcing Guide?

Products listed were identified while researching formulation type, manufacturer quality standards, standardisation of the active compound, and practical availability. The highlighted Featured Product is the retail option that, in my opinion, most closely met the stated selection criteria among the products reviewed. In many cases, they are products I personally purchased for my partner after comparing the information available from manufacturers, retailers, testing documentation, and published research. It is not a guarantee that the product is suitable for every individual.

Is Mechanica Natura independent?

Yes. Mechanica Natura is independently produced and is not owned, funded, sponsored, or commissioned by any supplement manufacturer, retailer, or brand. Some product links participate in affiliate programmes, which means the site may earn a commission if a purchase is made through them, at no additional cost to the reader. These relationships do not influence which products are included, how the evidence is assessed, or which product is highlighted; many products featured on the site do not offer affiliate programmes and are included because they were the preferred option based on the sourcing criteria used. Further details are available in the Affiliate Disclosure.

Who writes Mechanica Natura?

Mechanica Natura is written and maintained by its founder, Adrianna, who is not a doctor, scientist, or researcher by profession. The site grew from the personal research she began after her partner was diagnosed with cancer. Its purpose is not to offer clinical expertise, but to organise published evidence carefully, explain it plainly, and be transparent about what the evidence can—and cannot—tell us. You can read more about the story behind the site on the About page.

How current is the information, and how often is it updated?

Each page reflects the evidence reviewed at the time it was prepared and is refreshed periodically. Science moves quickly, and no static resource can capture every development in real time. Publication dates and linked references are provided so readers can review the underlying sources directly, and any decision that depends on current clinical guidance should be confirmed with a qualified healthcare professional.

Does Mechanica Natura recommend taking nutraceuticals during cancer treatment?

No. Nutraceuticals can interact with medicines, affect drug-metabolising enzymes, alter bleeding risk, or be unsuitable in particular clinical circumstances. Mechanica Natura presents published evidence and flags known or plausible safety concerns, but decisions about supplement use during treatment should be made with a qualified doctor or other healthcare professional who knows the individual’s diagnosis, treatment plan, and medical history.

Have a question that is not answered here?

If there is something you would like to understand better, or an explanation you think could be clearer, you are welcome to contact mechanicanatura@gmail.com. Mechanica Natura cannot answer personal medical questions or advise on individual treatment, but general questions about the site, its Functional Framework, sourcing process, or how to interpret the evidence are always welcome.